The neuroscience of gratitude: How saying "Thank You" changes your brain!


Imagine this: You’re walking down the street and a stranger holds the door open for you. You smile and say, “Thank you!” instantly feeling a small rush of warmth. It’s a simple exchange, but did you know that in that moment your brain is working overtime? That “thank you” you just said is doing more than just making someone’s day — it’s actively changing the way your brain works.

Welcome to the fascinating world of neuroscience, where gratitude isn’t just a nice feeling — it’s a biological game-changer. It turns out, being thankful does some pretty magical things to your brain, and the best part? You don’t need to do anything complicated to get the benefits. Let’s dive into the science behind this positive emotion and discover how it can make your brain and your life a little bit better.

The roots of all goodness lie in the soil of appreciation for goodness.
— Dalai Lama

Gratitude lights up your brain’s reward system

Here’s the fun part: when you express gratitude, your brain lights up like a Christmas tree — and we’re not talking about metaphorical lights. We’re talking about the reward center of your brain: the same area that responds when you eat chocolate, win a game or get a nice bonus. That’s because gratitude activates the region responsible for dopamine production.

Dopamine - the "feel-good" neurotransmitter. It makes you feel happy, motivated and satisfied. So when you say “thank you,” your brain is rewarding you with a natural high. It’s like your brain is saying, “Hey, that was a good thing you just did — let’s feel awesome about it!” And here’s the kicker: the more you express gratitude, the more dopamine your brain releases, creating a cycle of positivity that reinforces itself.


Gratitude helps you build emotional resilience

Life isn’t always sunshine and rainbows. We all face challenges — stress, anxiety and those rough days where nothing goes right. Practicing gratitude can help you bounce back from these tough moments faster.

Here’s why: Gratitude activates the prefrontal cortex, the part of the brain responsible for decision-making, emotional regulation and rational thinking. By engaging this area, gratitude can reduce activity in the amygdala, the brain’s “fear center” that responds to stress and danger.

So, when you focus on what you’re grateful for, even in the middle of a stressful day, you’re essentially teaching your brain to calm down. Gratitude acts like an emotional buffer, making it easier for you to manage negative emotions and cope with stress more effectively.

Let us be grateful to people who make us happy; they are the charming gardeners who make our souls blossom
— Marcel Proust, French writer

The “Gratitude Effect” — more than just a happy feeling

But wait, it gets better! People who regularly practice gratitude show structural changes in their brains. Those who write down what they are thankful for show an increase in grey matter in the left prefrontal cortex. This area is linked to positive emotions, social interactions and goal-setting.

In simple terms? Practicing gratitude doesn’t just make you feel good in the moment — it physically alters the way your brain is wired, making you more likely to experience positive emotions and foster strong social bonds in the long run. It’s like brain training, but instead of lifting weights, you’re lifting your mood!


Gratitude boosts your relationships (and your brain!)

Here’s something truly amazing: being grateful doesn’t just benefit you. It also has a positive impact on those around you. When you express gratitude to others — thanking a colleague for their help or showing appreciation to a friend — you strengthen the social bonds that keep relationships thriving. And in turn, these connections stimulate brain areas related to empathy and trust.

When you express gratitude, your brain releases oxytocin - the bonding hormone. It plays a key role in building trust, empathy and connection. It’s the same hormone released when you hug someone or cuddle with your pet. So by saying “thank you” and acknowledging others, you’re not only making yourself feel good — you’re also creating a ripple effect that boosts social harmony and cooperation.

When we give cheerfully and accept gratefully, everyone is blessed.
— Maya Angelou, American poet and author


Gratitude and health: more than just a feel-good habit

The benefits of gratitude don’t stop at the brain — they extend to your body too! Practicing gratitude can improve overall physical health as people who kept a gratitude journal experienced fewer health problems, slept better and even have lower blood pressure. Gratitude reduces stress, which can lower inflammation and improve heart health.

But it’s not just about being thankful for the big things in life. Those who find small things to be grateful for — like the warmth of the sun or a delicious cup of coffee — tend to be healthier, happier, and more satisfied with life. So when you feel grateful, your brain and body are both in on the act, working together to make you healthier and more resilient.

Do try this at home: make gratitude a daily habit!

You might be wondering: “How can I start reaping the benefits of gratitude?” Here are some simple ways to make gratitude a daily habit:

  1. Gratitude Journaling: Spend five minutes each day writing down three things you’re grateful for. They can be big (like your health) or small (like the smell of fresh bread). This helps retrain your brain to focus on the positive.

  2. Express Appreciation: Tell people you appreciate them, whether it’s a quick “thank you” or a heartfelt note. You’ll make their day — and yours!

  3. Mindfulness: Practice mindfulness by taking a moment each day to pause and appreciate what you have in the present moment. Close your eyes, take a deep breath and reflect on the good things in your life.

Gratitude is the wine for the soul. Go on. Get drunk.
— Rumi, Persian poet and mystic

Gratitude is contagious (so spread it around!)

Here’s the cherry on top: gratitude is contagious! When you express appreciation, you encourage others to do the same. It’s a ripple effect that spreads positivity, boosts relationships and makes everyone’s brains a little bit happier. So, the more you practice gratitude, the more you help create a world where others feel encouraged to be thankful too.

Now, go ahead and say it: thank you. Your brain will thank you back!

I hope you enjoyed this article and got inspired to improve your wellbeing by expressing gratitude and appreciating everyone and everything around you. Get in touch, I have plenty more in stock!

Previous
Previous

Enhancing communication with the SCARF model

Next
Next

Unlocking your brain's superpowers: How two models can help you make smarter decisions